Cosmetics

HRIPT & Ophthalmic Tolerance for a Sensitive-Skin Serum

Focus Area

Cosmetics

Duration

3 months

Footprint

1 dermatology unit

Key Outcome

Non-irritating, non-sensitizing claim

Overview

A dermatology-led safety and tolerance study delivered claim-ready evidence for a sensitive-skin serum across dermal patch, HRIPT and ophthalmic tolerance modules.

The Challenge

What we were asked to solve

A global beauty brand needed clean, cruelty-free human safety evidence for a sensitive-skin serum before EU/UK launch — spanning dermal patch, HRIPT and ophthalmic tolerance.

Our Approach

How we delivered it

1Human Repeat Insult Patch Test (HRIPT) on 55 subjects
248-hour occlusive patch test + instrumental erythema scoring
3Ophthalmic tolerance under investigator supervision
4Consumer perception via validated dermatology ePRO

Outcomes

Non-irritating, non-sensitizing claim

Non-irritating and non-sensitizing under HRIPT criteria

Ophthalmic tolerance graded as acceptable across all subjects

Consumer perception score 8.6/10 for comfort and finish

Full report accepted for EU CPNP dossier without revisions

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